August 21, 2025- New Cleveland Clinic-led research has shown that a bundled system of technology-driven interventions – leveraging artificial intelligence (AI) to deliver personalized health insights and lifestyle recommendations – can improve glycemic control in adults with Type 2 diabetes.
Findings published in the New England Journal of Medicine Catalyst showed that 71% of study participants using the bundled intervention system met the primary endpoint of achieving an A1C of 6.5% with fewer medications. Kevin M. Pantalone, D.O., Director of Diabetes Initiatives at Cleveland Clinic and a professor of medicine at Cleveland Clinic Lerner College of Medicine, served as the primary investigator for this study.
Developed by Twin Health, the bundled intervention system (called Twin Precision Treatment) monitors real-time health metrics collected from a patient’s wearable sensors and Bluetooth-connected devices and includes human telecoaching. The system continuously tracks real-time health metrics – such as blood glucose levels, weight, blood pressure, physical activity and sleep – using data from wearable sensors and Bluetooth-connected devices (including a continuous glucose monitor).