June 8, 2026- Mayo Clinic researchers and collaborators have shown that artificial intelligence (AI) can analyze routine pathology slides to help classify meningiomas, the most common primary brain tumor in adults, and predict a patient’s risk of tumor recurrence.
The study, published in The Lancet Digital Health, demonstrates that deep learning models can extract molecular and prognostic information from standard hematoxylin and eosin, or H&E, slides — the same type of tissue images already used in routine clinical care. These insights are typically obtained through DNA methylation profiling, an advanced genetic test which provides valuable diagnostic and prognostic information but can be costly, time-consuming and is unavailable in many hospitals.