January 28, 2026- A new study by American Cancer Society (ACS) researchers shows that overall cancer mortality in people younger than 50 in the United States has decreased by 44%, from 25.5 per 100,000 people in 1990 to 14.2 in 2023. The progress is due to declines in mortality for four of the five leading cancer-related deaths (breast, lung, and brain cancers, and leukemia). Only colorectal cancer (CRC) mortality increased, by 1.1% per year since 2005, advancing it from the fifth most common cancer death in the early 1990s to first in 2023. The study is to be published in the Journal of the American Medical Association (JAMA).
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